Drusenoid Pigment Epithelial Detachment: Genetic and Clinical Characteristics
نویسندگان
چکیده
منابع مشابه
Clinical features of drusenoid pigment epithelial detachment in age related macular degeneration.
AIM To analyse clinical features of drusenoid pigment epithelium detachment (PED) in age related macular degeneration. METHODS 61 eyes of 32 patients with untreated drusenoid PED were followed for an average of 4.6 years (range 1-17 years). Drusenoid PED was defined as (1/2) disc diameter (DD) of confluent soft drusen under the centre of the macula. All patients underwent visual acuity measur...
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We report the clinical course of photodynamic therapy (PDT) in a patient with drusenoid pigment epithelium detachment (PED). A patient with drusenoid PED underwent PDT follow-up was carried out at one week, one month, three months, six months and one year after treatment. Fundus exam, optical coherence tomography (OCT) and fluorescein angiography were performed. After the PDT, drusen and PED we...
متن کاملIntravitreal ranibizumab for symptomatic drusenoid pigment epithelial detachment without choroidal neovascularization in age-related macular degeneration
BACKGROUND The aim of our study was to evaluate the functional and anatomic outcomes of intravitreal ranibizumab for the treatment of symptomatic drusenoid pigment epithelial detachment without choroidal neovascularization in age-related macular degeneration. METHODS This was a prospective, single-center, uncontrolled, interventional pilot study. Six consecutive eyes (six patients) with druse...
متن کاملAssociations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments
Purpose Drusenoid pigment epithelial detachments (PEDs) are a defined path to atrophy in age-related macular degeneration (AMD). We analyzed the relationships between retinal pigment epithelium (RPE) and drusen volume changes during the PED lifecycle, using spectral-domain optical coherence tomography (SD-OCT). Methods Twenty-one cases of drusenoid PED tracked using SD-OCT through periods of ...
متن کاملThe onset of pigment epithelial proliferation after retinal detachment.
The adult mammalian retinal pigment epithelium (RPE) is mitotically inactive, yet retains the capacity to proliferate under certain conditions. To determine the onset of RPE proliferation after retinal detachment, we examined experimentally detached cat retinas of 12, 24, 48, and 72 hr duration. An additional animal served as a nondetached, sham-operated control. 3H-thymidine was injected into ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22084074